I decided to jump on the bandwagon of Twitter, to see what it may be able to do for me and getting into the community a bit more. You can follow me, at
http://twitter.com/derickbailey
For my client, I've installed Twhirl, which uses Adobe AIR as it's platform.
http://twhirl.org/
It's a pretty nice client, so far. Easy to setup and use. Thought it's my first Twitter client, so I don't really have anything to compare it to, other than standard IM clients.